Apixaban Davis Pdf in 2021

Acts as a selective, reversible factor Xa inhibitor of the site, inhibiting both the free and bound factor.

Does not directly affect platelet aggregation, but does inhibit thrombin-induced platelet aggregation. Decreases thrombin generation and thrombin development.

Indications
Decreases the risk of stroke / systemic embolism associated with non-valvular atrial fibrillation.

Preventing deep vein thrombosis that may lead to pulmonary embolism following knee or hip replacement surgery.

Treatment and reduction of risk of recurrence of deep vein thrombosis ( DVT) or pulmonary embolism ( PE).

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